![]() Reports of recreational use began to surface shortly after its appearance on the online research chemical market in the 2010s. Nichols in 1999 proposed its potential use as an alternative to psilocybin for pharmacological research due to the lower cost of synthesis. It is unknown when it was first explored in humans. However, it was not tested for psychoactivity during this time. ![]() 4-AcO-DMT is thought to produce its effects by binding to serotonin receptors in the brain however, the precise mechanism is not known.Ĥ-AcO-DMT was first synthesized in 1963 by Albert Hofmann and Franz Troxler as part of a chemical investigation into psilocin analogs. ![]() It is structurally related to psilocybin and psilocin, the active ingredient in psilocybin mushrooms ("magic mushrooms"). It is not a recommendation and should be verified with other sources for accuracy.Ĥ-Acetoxy-N,N-dimethyltryptamine (also known as 4-AcO-DMT, 4-Acetoxy-DMT, O-Acetylpsilocin, psilacetin, and "synthetic mushrooms") is a novel lesser-known psychedelic substance of the tryptamine class. See responsible use section.ĭISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. 4-AcO-DMT, 4-Acetoxy-DMT, Psilacetin, O-Acetylpsilocin, Synthetic mushroomsģ-1H-indol-4-yl acetate
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